New Products
The projects encompass precompetitive, innovative, and industrially relevant research, which makes a future transfer of technologies and knowledge in Saxony-Anhalt possible. An interdisciplinary approach is pursued, connecting innovative theoretical with experimental approaches.
The planned project contents encompass the efficient development of innovative chemical products. DUB inhibitors, recyclable polymers, and functionalized particle systems are highly innovative product classes, which suggest a very high value-creation for the chemical-pharmaceutical industry in Saxony-Anhalt. The development processes for these product classes, from the molecule design to the testing to the production, are still lengthy and costly. Therefore, work is in progress to drastically accelerate product development with computer-based methods.
In the development of innovative products, the focus is on the generation of DUB inhibitors, which are to be used as a new class of therapeutics for the treatment of different inflammatory diseases and cancer types. In the combination of the working hypothesis and molecular modeling for the prediction of structure-property relations new synthesis ways for high-quality therapeutics are to be developed. For this purpose fast and innovative test procedures in primary cell cultures (mucosoids) are applied for the experimental validation of DUB inhibitors.
Further project areas aim for new recycable plastics (consisting of polymers) and high-quality particulate products. In the area of new recycable plastics, the focus is on the establishment of new molecule structures, which serve the purpose of reducing the exertion during the depolymerization in support of a circular economy. Here biobased polymers are especially promising and innovative. In the area of particulate products the methods developed in the project area “New computer tools for process design and process management” are to be utilized for the production of high-quality particles with defined properties, to systematically reduce lengthy experimental investigations, which are typically used in this area.